BETTER Life will establish a European Digital Centre of Excellence for fostering Socially Engaged Research (SER) in Life Sciences, as well as seven regional centres operating in their surrounding ecosystems.This inter-institutional support structure addresses the lack of collaboration between early career researchers and the non-academic sectors by designing tools, standards, and framework conditions under the umbrella of the EU centre and implementing these solutions in the regional ecosystems. The project aims to support the development of inter-institutional capacities by establishing an EU BETTER Life coordination centre that will generate transferable tools and standards. At an intra-institutional level, the project creates local centres guided by a framework to follow the regional customization implementation. At an individual level, the regional centres develop capacities by training early career researchers and establishing a community of practice in each surrounding ecosystem. For that purpose, the centre is based on the quadruple helix model of innovation, where the interaction of academic, research, industry, government, and society generate mutually beneficial partnerships.